Cizinate: How It Works and What to Expect

Cizinate tablets are a widely used medication designed to combat nausea, vomiting, and dizziness, particularly in cases of motion sickness and vertigo. Understanding how this medication works and what you can expect from its usage is essential for anyone considering this treatment.

How Cizinate Works

These tablets contain the active ingredient cinnarizine, an antihistamine that works by blocking histamine and certain receptors in the brain. This action helps to prevent the brain from receiving signals that trigger nausea and vomiting. 

  1. Histamine Blockade: One chemical in the body that is involved in both gut regulation and allergic reactions is histamine. The drug helps lessen the body’s reaction to motion and imbalance, which are frequent causes of nausea and vomiting, by blocking histamine receptors.
  2. Calcium Channel Blocking: Additionally, cinnarizine blocks calcium channels. It assists in maintaining the stability of blood vessels in the inner ear by preventing the entry of calcium ions into cells. The tablets are useful for balance disorders because this stabilization aids in the management of vertigo and dizziness symptoms.
  3. Vestibular System Regulation: Balance and spatial orientation are maintained by the vestibular system of the inner ear. The medication works by modulating the activity of this system to help prevent the abnormal signals that cause vertigo and related symptoms.

What to Expect

When taking this medication, understanding what to expect can help manage your experience and ensure you use it effectively.

  1. Dosage and Administration: The tablets are usually taken orally, with the dosage depending on the condition being treated. For motion sickness, it is typically recommended to take the tablet about 30 minutes to an hour before traveling. For vertigo, the dosage might be different and should be followed as prescribed by a healthcare professional.
  2. Onset of Action: The medication begins to work relatively quickly, often within 30 minutes to an hour. This rapid onset makes it a convenient option for those needing prompt relief from nausea or dizziness.
  3. Duration of Effect: The effects can continue for a few hours, offering consistent symptom relief. To preserve its efficacy, it’s crucial to adhere to the recommended dosage schedule.
  4. Common Side Effects: Like all medications, these tablets can cause side effects. The most common include drowsiness, dry mouth, and sometimes blurred vision. These side effects are generally mild but can affect daily activities, particularly if operating heavy machinery or driving.
  5. Possible Allergic Reactions: Rarely, allergic reactions such as rash, itching, or swelling can occur in some people. Seeking prompt medical attention is imperative in the event of any severe reactions.
  6. Interactions with Other Medications: This medication can interact with other drugs, particularly those that also cause drowsiness or have anticholinergic effects. Always consult with a healthcare provider before combining it with other treatments to avoid adverse interactions.
  7. Suitability for Different Populations: The tablets are not suitable for everyone. Individuals with conditions like glaucoma, urinary retention, or severe liver disease should avoid them. Pregnant or breastfeeding women should consult their doctor before use to ensure it is safe.


Cizinate is an effective treatment for vertigo-related nausea, motion sickness, vomiting, and dizziness. Users can minimize potential drawbacks and maximize benefits by understanding how it works and what to expect. Before starting any new medication, consult with your healthcare provider to ensure that it is appropriate for your specific needs. When used correctly, Cizinate can significantly reduce unpleasant symptoms while also improving many people’s quality of life.


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